Structural and functional studies of the metalloendopeptidase (EC 3.4.24.15) involved in degrading gonadotropin releasing hormone.
作者信息
Glucksman M J, Orlowski M, Roberts J L
机构信息
Fishberg Research Center for Neurobiology, Mount Sinai School of Medicine, New York, New York 10029.
出版信息
Biophys J. 1992 Apr;62(1):119-22. doi: 10.1016/S0006-3495(92)81798-8.
Abstract
摘要
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Structure of thermolysin refined at 1.6 A resolution.在1.6埃分辨率下精修的嗜热菌蛋白酶结构。
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Primary structure homologies between two zinc metallopeptidases, the neutral endopeptidase 24.11 ("enkephalinase") and thermolysin, through clustering analysis.
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Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.分子克隆揭示人血管紧张素I转换酶中的两个推定活性中心。
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Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides.来自大鼠睾丸的内肽酶24.15。该酶的分离及其对合成肽和天然肽（包括含脑啡肽的肽）的特异性。
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Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA.
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