Bittencourt A L, Mendonça N, de Freitas L A, Schnitzer B
Department of Pathology, Hospital Martagão Gesteira, Salvador, Bahia, Brazil.
Pediatr Dermatol. 1992 Jun;9(2):117-22. doi: 10.1111/j.1525-1470.1992.tb01226.x.
An 8-year-old boy was seen with a cutaneous Ki-1 anaplastic, large cell lymphoma with multiple lesions. Some of the lesions showed spontaneous regression. During more than seven years of disease no systemic involvement was observed, but recurrent, self-healing lesions did appear. Histopathologic examination of five lesions revealed a variety of findings, from an inflammatory infiltrate to a highly anaplastic pattern. The neoplastic cells expressed Ki-1 and leukocyte common antigens. Ultrastructurally, those cells showed ruffled indentations. The differential diagnosis includes microvillous malignant lymphoma. The patient has had a four-year follow-up without relapses.
一名8岁男孩被诊断为患有皮肤Ki-1间变性大细胞淋巴瘤，有多处病损。部分病损出现自发消退。在超过七年的病程中，未观察到全身受累情况，但确实出现了复发且可自愈的病损。对五个病损进行组织病理学检查发现了多种表现，从炎症浸润到高度间变模式。肿瘤细胞表达Ki-1和白细胞共同抗原。超微结构上，这些细胞显示有皱襞状凹陷。鉴别诊断包括微绒毛恶性淋巴瘤。该患者已进行了四年随访，无复发。
