Kanekura T, Setoyama M, Yotsumoto S, Nishi M, Tashiro M
Department of Dermatology, Faculty of Medicine, Kagoshima University, Japan.
J Dermatol. 1991 Jun;18(6):345-51. doi: 10.1111/j.1346-8138.1991.tb03096.x.
A 55-year-old female with a complaint of tumors on the right lower extremity was reported. The condition was diagnosed as anaplastic large cell lymphoma, so-called Ki-1 lymphoma, by its histological and immunohistochemical features. The clonal proliferation of the infiltrating cells of the skin lesions was confirmed by the analysis of T cell receptor gene rearrangement. The lesions have repeatedly occurred on the right lower extremity for more than ten years. In this report, we also discuss the prognosis of anaplastic large cell lymphoma with or without skin lesions.
报告了一名55岁女性，其主诉右下肢有肿瘤。根据组织学和免疫组化特征，该病症被诊断为间变性大细胞淋巴瘤，即所谓的Ki-1淋巴瘤。通过T细胞受体基因重排分析证实了皮肤病变浸润细胞的克隆性增殖。这些病变在右下肢反复出现已达十多年。在本报告中，我们还讨论了有或无皮肤病变的间变性大细胞淋巴瘤的预后。
