马动脉炎病毒：概述
Equine arteritis virus: an overview.
作者信息
Chirnside E D
机构信息
Department of Infectious Diseases, Animal Health Trust, Suffolk.
出版信息
Br Vet J. 1992 May-Jun;148(3):181-97. doi: 10.1016/0007-1935(92)90044-2.
Abstract
The causative agent of the respiratory disease equine viral arteritis is a small, single-stranded RNA virus with a genome organization and replication strategy related to that of coronaviruses and toroviruses. Clinical signs of infection in horses vary widely and severe infection can lead to pregnant mares aborting. Infected horses generally make good recoveries but stallions may become semen shedders of equine arteritis virus (EAV). These carrier stallions play an important role in the dissemination and perpetuation of EAV. Laboratory tests exist to detect virus and the equine immune response to infection. However, vaccines are not currently licensed in the UK to combat viral arteritis, the incidence of which may increase due to changes in European legislation.
摘要
马病毒性动脉炎这种呼吸道疾病的病原体是一种小型单链RNA病毒，其基因组结构和复制策略与冠状病毒及环曲病毒相关。马感染后的临床症状差异很大，严重感染可导致怀孕母马流产。受感染的马通常恢复良好，但种公马可能会成为马动脉炎病毒（EAV）的精液排出者。这些携带病毒的种公马在EAV的传播和持续存在中起着重要作用。现有实验室检测方法可用于检测病毒以及马对感染的免疫反应。然而，目前英国尚未批准用于对抗病毒性动脉炎的疫苗，由于欧洲立法的变化，该病的发病率可能会上升。
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