Clinical effects of the dichloro and monochlorophenyl analogues of diamino pyrimidine: antagonists of folic acid.
作者信息
MURPHY M L, ELLISON R R, KARNOFSKY D A, BURCHENAL J H
出版信息
J Clin Invest. 1954 Oct;33(10):1388-96. doi: 10.1172/JCI103016.
Abstract
摘要
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Br Med J. 1952 Apr 5;1(4761):732-4. doi: 10.1136/bmj.1.4761.732.
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A simple method for determination of levels of amethopterin in blood and urine.
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The effects of the folic acid antagonists and 2,6-diaminopurine on neoplastic disease, with special reference to acute leukemia.
Cancer. 1951 May;4(3):549-69. doi: 10.1002/1097-0142(195105)4:3<549::aid-cncr2820040308>3.0.co;2-j.
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Prevention of toxicity of massive doses of A-methopterin by citrovorum factor.
Proc Soc Exp Biol Med. 1951 Feb;76(2):382-4. doi: 10.3181/00379727-76-18497.
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Hyperpigmentation in acute leukemia treated with folic acid antagonists.使用叶酸拮抗剂治疗的急性白血病中的色素沉着过度。
Proc Soc Exp Biol Med. 1950 Nov;75(2):332-4. doi: 10.3181/00379727-75-18189.
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Effect of various compounds on the Ehrlich ascites carcinoma.各种化合物对艾氏腹水癌的作用。
Cancer Res. 1953 Jun;13(6):431-41.
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Distribution of amethopterin in normal mouse tissues following intravenous injection.静脉注射后氨甲蝶呤在正常小鼠组织中的分布。
Proc Soc Exp Biol Med. 1952 Oct;81(1):193-6. doi: 10.3181/00379727-81-19818.
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The pharmacological properties of 2, 4-diamino-5-p-chlorophenyl-6-ethylpyrimidine, daraprim.2,4-二氨基-5-对氯苯基-6-乙基嘧啶（达拉匹林）的药理学特性。
J Pharmacol Exp Ther. 1953 Jan;107(1):92-130.
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Antagonists of nucleic acid derivatives. VII. 2, 4-Diaminopyrimidines.核酸衍生物的拮抗剂。VII. 2,4-二氨基嘧啶。
J Biol Chem. 1952 Nov;199(1):43-56.
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2, 4-Diaminopyrimidines as antagonists of folic acid and folinic acid.
Arch Biochem Biophys. 1952 Oct;40(2):479-81. doi: 10.1016/0003-9861(52)90138-0.
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