巨噬细胞在无抗体情况下吞噬包被细菌的机制。
The mechanisms by which macrophages phagocyte encapsulated bacteria in the absence of antibody.
作者信息
SAWYER W D, SMITH M R, WOOD W B
出版信息
J Exp Med. 1954 Oct 1;100(4):417-24. doi: 10.1084/jem.100.4.417.
Abstract
EVIDENCE HAS BEEN PRESENTED
(1) that macrophages from experimentally produced inflammatory exudates are capable of phagocyting fully encapsulated Type I pneumococci and group A Friedländer's bacilli in the absence of antibody, (2) that the principal mechanisms involved are those of surface phagocytosis, and (3) that the majority of pneumococci ingested by macrophages in antibody-free preparations are ultimately destroyed. The relationship of these phenomena to the mechanism of recovery in pneumococcal and Friedländer's bacillus infections has been briefly discussed.
摘要
已有证据表明
（1）实验性产生的炎性渗出物中的巨噬细胞能够在无抗体的情况下吞噬完全包膜化的I型肺炎球菌和A群弗里德兰德氏杆菌；（2）所涉及的主要机制是表面吞噬作用；（3）在无抗体制剂中被巨噬细胞摄取的大多数肺炎球菌最终会被破坏。已简要讨论了这些现象与肺炎球菌和弗里德兰德氏杆菌感染恢复机制的关系。
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