食管癌的超微结构：多向分化。43例病例的透射电子显微镜研究。

The ultrastructure of oesophageal carcinomas: multidirectional differentiation. A transmission electron microscopic study of 43 cases.

作者信息

Newman J, Antonakopoulos G N, Darnton S J, Matthews H R

机构信息

Department of Histopathology, East Birmingham Hospital, U.K.

出版信息

J Pathol. 1992 Jun;167(2):193-8. doi: 10.1002/path.1711670206.

DOI:10.1002/path.1711670206

PMID:1321902

Abstract

Forty-three oesophageal carcinomas, comprising 15 squamous cell carcinomas, 22 adenocarcinomas, 5 small cell carcinomas, and 1 adenosquamous carcinoma, were examined by transmission electron microscopy. The ultrastructural features of each tumour type are detailed. Multi-directional differentiation (heterogeneity) was observed in 11 cases: 5 squamous cell carcinomas with focal glandular features; 4 adenocarcinomas with focal squamous features; and 2 small cell carcinomas, one with glandular and the other with squamous features. Abnormal distributions of desmosomes in squamous cell carcinomas and of polarity of tumour cells in adenocarcinomas are described.

摘要

对43例食管癌进行了透射电子显微镜检查，其中包括15例鳞状细胞癌、22例腺癌、5例小细胞癌和1例腺鳞癌。详细描述了每种肿瘤类型的超微结构特征。在11例中观察到多向分化（异质性）：5例鳞状细胞癌具有局灶性腺性特征；4例腺癌具有局灶性鳞状特征；2例小细胞癌，1例具有腺性特征，另1例具有鳞状特征。描述了鳞状细胞癌中桥粒的异常分布以及腺癌中肿瘤细胞的极性异常。