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大鼠胸主动脉中膜去分化平滑肌细胞上CGRP受体的表达情况。

Occurrence of CGRP receptors on dedifferentiated smooth muscle cells from media of rat thoracic aorta.

作者信息

Connat J L, Thievent A, Carrier N, Huggel H

机构信息

Anatomie et Physiologie Comparées, Université de Genève, Switzerland.

出版信息

Ann N Y Acad Sci. 1992 Jun 30;657:444-8. doi: 10.1111/j.1749-6632.1992.tb22795.x.

DOI:10.1111/j.1749-6632.1992.tb22795.x
PMID:1322099
Abstract

Autoradiographic studies with [125I]-CGRP did not demonstrate receptors on sections from two different regions of 5-week-old rat aorta (of both sexes). By contrast, cultured smooth muscle cells isolated from similar aortic media and passaged 5 to 7 times exhibited specific binding.

摘要

用[125I]-降钙素基因相关肽进行的放射自显影研究未在5周龄大鼠主动脉(雌雄皆有)两个不同区域的切片上显示出受体。相比之下,从类似主动脉中膜分离并传代5至7次的培养平滑肌细胞表现出特异性结合。

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引用本文的文献

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Receptors mediating CGRP-induced relaxation in the rat isolated thoracic aorta and porcine isolated coronary artery differentiated by h(alpha) CGRP(8-37).介导大鼠离体胸主动脉和猪离体冠状动脉中降钙素基因相关肽(CGRP)诱导舒张的受体可被人αCGRP(8-37)区分。
Br J Pharmacol. 1999 Sep;128(2):283-92. doi: 10.1038/sj.bjp.0702764.
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Postnatal development of the rat portal vein: correlation with occurrence of peptidergic innervation.大鼠门静脉的出生后发育:与肽能神经支配发生的相关性。
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