Pasiukova E G, Nuzhdin S V
Genetika. 1992 Apr;28(4):5-18.
Considerable heterogeneity of retrotransposon copia sites of location on polytene chromosomes was revealed in one of the substocks of the inbred Drosophila melanogaster stock. Heterogeneity of copia sites of location was found in no other substocks analyzed. The heterogeneity was shown to be caused by copia insertions in new sites. The frequency of insertions is about 12% per haploid genome per generation. The retrotransposon excisions and somatic transpositions were not observed. The location of retrotransposons mdg1, mdg2, mdg3, mdg4, 297 and H.M.S. Beagle appeared to be stable in all the stocks analyzed. Thus, a model system allowing to study mechanisms of retrotransposon copia transpositions in D. melanogaster tissues as well as phenotypic effects of copia mobilization is described.
在近交黑腹果蝇品系的一个亚系中，揭示了多线染色体上反转录转座子copia位点位置的显著异质性。在分析的其他亚系中未发现copia位点位置的异质性。这种异质性被证明是由copia插入新位点引起的。插入频率约为每代单倍体基因组12%。未观察到反转录转座子的切除和体细胞转座。在所有分析的品系中，反转录转座子mdg1、mdg2、mdg3、mdg4、297和H.M.S. Beagle的位置似乎是稳定的。因此，描述了一个模型系统，该系统可用于研究黑腹果蝇组织中反转录转座子copia转座的机制以及copia动员的表型效应。
