电离辐射对吞噬作用及血液杀菌能力的影响。一、辐射对白细胞迁移的影响。
The effect of ionizing radiation on phagocytosis and the bactericidal power of the blood. I. The effect of radiation on migration of leucocytes.
作者信息
SHECHMEISTER I L, FISHMAN M
出版信息
J Exp Med. 1955 Mar 1;101(3):259-74. doi: 10.1084/jem.101.3.259.
Exposure of rats to 600 r total body radiation did not influence either the rate or the extent of migration of their leucocytes 1 day after irradiation, but did decrease their migration on the 2nd and the 5th postirradiation day. Migration of rat leucocytes was not altered by infection of the animal with M. aureus. Leucocytes of rabbits irradiated with 100 r showed a normal rate and extent of migration. However rabbits exposed to 500 r or 800 r showed depression of leucocyte migration at two postirradiation intervals, on the 3rd to 5th and the 10th to 13th days after irradiation, with normal activity intervening. By the 21st postirradiation day the ability of leucocytes to migrate returned to normal. The effect of radiation on total and differential W.B.C. counts and the relationship of this effect to migration is discussed. The decrease in leucocyte migration could not be ascribed either to leucopenia or to plasma factors.
给大鼠全身照射600伦琴的辐射，在照射后1天对其白细胞迁移的速率或程度均无影响，但在照射后第2天和第5天会使其迁移减少。用金黄色葡萄球菌感染动物，大鼠白细胞的迁移未发生改变。接受100伦琴照射的兔白细胞显示出正常的迁移速率和程度。然而，接受500伦琴或800伦琴照射的兔在照射后的两个时间段，即照射后第3至5天和第10至13天，白细胞迁移受到抑制，中间有正常活性期。到照射后第21天，白细胞的迁移能力恢复正常。讨论了辐射对白细胞总数和分类计数的影响以及这种影响与迁移的关系。白细胞迁移的减少既不能归因于白细胞减少，也不能归因于血浆因子。
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