Laboratories of The Rockefeller Institute for Medical Research.
J Exp Med. 1950 Mar 31;91(4):381-92. doi: 10.1084/jem.91.4.381.
A description is given of a slide cell whereby the rate of migration of very small amounts of leucocytes can be followed and measured. The migration of polymorphonuclear leucocytes was found to be inhibited by virulent tubercle bacilli pathogenic for the class of animal (mammal or bird) from which the leucocytes were obtained; it was not affected by the avirulent variants of these microorganisms, or by bacilli pathogenic for animals of the other class. Tests failed to disclose that the inhibition of leucocytic migration resulted from any gross damage caused by the bacilli to the leucocytes.
介绍了一种滑动细胞,通过该细胞可以跟踪和测量非常少量白细胞的迁移率。发现多形核白细胞的迁移被来自其来源动物(哺乳动物或鸟类)的有致病性的毒力结核分枝杆菌所抑制;它不受这些微生物的无毒变体或对另一类动物具有致病性的杆菌的影响。试验未能表明白细胞迁移的抑制是由杆菌对白细胞造成的任何严重损伤引起的。