对经对氯苯丙氨酸处理后的大鼠小脑进行N-乙酰血清素的免疫组织学研究。
Immunohistological investigation of N-acetylserotonin in the rat cerebellum after parachlorophenylalanine treatment.
作者信息
Bubenik G A, Brown G M, Grota L J
出版信息
Experientia. 1976 May 15;32(5):579-81. doi: 10.1007/BF01990173.
PMID:132358
Abstract
The amount of N-acetylserotonin (NAS) in the granule layer of the rat cerebellum was investigated using immunolohistologic double antibody technique. After 5 days of treatment with parachlorophenylalanine (PCPA) an increase of NAS was observed. The possibility of a differential effect of PCPA on serotonin synthesis in the neurons and the nerve terminals is discussed.
摘要
采用免疫组织化学双抗体技术研究了大鼠小脑颗粒层中N-乙酰血清素（NAS）的含量。用对氯苯丙氨酸（PCPA）处理5天后，观察到NAS增加。讨论了PCPA对神经元和神经末梢中血清素合成产生差异效应的可能性。
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