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5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor.

作者信息

Charalambous A, Yan G, Houston D B, Howlett A C, Compton D R, Martin B R, Makriyannis A

机构信息

School of Pharmacy, University of Connecticut, Storrs 06269.

出版信息

J Med Chem. 1992 Aug 7;35(16):3076-9. doi: 10.1021/jm00094a023.

DOI:10.1021/jm00094a023
PMID:1323683
Abstract
摘要

相似文献

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5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor.
J Med Chem. 1992 Aug 7;35(16):3076-9. doi: 10.1021/jm00094a023.
2
Detection of cannabinoid receptors by photoaffinity labelling.通过光亲和标记法检测大麻素受体
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A novel electrophilic high affinity irreversible probe for the cannabinoid receptor.一种用于大麻素受体的新型亲电高亲和力不可逆探针。
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Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain.对Δ9-四氢大麻酚产生行为耐受性，但全脑大麻素受体结合或mRNA水平未发生改变。
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(-)-11-Hydroxy-7'-isothiocyanato-1',1'-dimethylheptyl-delta 8-THC: a novel, high-affinity irreversible probe for the cannabinoid receptor in the brain.
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Novel conformationally restricted tetracyclic analogs of delta8-tetrahydrocannabinol.新型δ8-四氢大麻酚的构象受限四环类似物。
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Enantioselective synthesis and pharmacology of 11-hydroxy-(1'S,2'R)-dimethylheptyl-delta 8-THC.
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Paradoxical pharmacological effects of deoxy-tetrahydrocannabinol analogs lacking high CB1 receptor affinity.
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Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice.阿片类药物和大麻素对δ-9-四氢大麻酚和吗啡依赖小鼠诱发戒断反应的调节作用
J Pharmacol Exp Ther. 2001 Sep;298(3):1007-14.

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