Watson B V, Brown W F
Department of Clinical Neurological Sciences, University Hospital, London, Ontario, Canada.
Muscle Nerve. 1992 Jul;15(7):768-73. doi: 10.1002/mus.880150704.
Eleven acute radial nerve palsies were examined between 3 days and 14 weeks following the onset of the neuropathy. Our objective was to quantify the relative extent of axon loss and conduction block in radial motor fibers supplying the extensor and abductor pollicis longus (EPL/APL) muscles. In 10 of 11 cases, conduction block exceeded axon loss. Maximum motor and sensory conduction velocities were normal distal to the spiral groove, suggesting that the larger myelinated fibers were not selectively involved in this acute neuropathy. The localization of the conduction block and slowing was, in every case, across the spiral groove. This method provides a relatively simple way of assessing the approximate contributions of axon loss and conduction block, and fits well with the early and usually complete clinical recovery in these cases.
在神经病变发作后的3天至14周内，对11例急性桡神经麻痹患者进行了检查。我们的目的是量化供应拇长伸肌（EPL）和拇长展肌（APL）的桡神经运动纤维中轴突损失和传导阻滞的相对程度。在11例中的10例中，传导阻滞超过了轴突损失。螺旋沟远端的最大运动和感觉传导速度正常，这表明较大的有髓纤维在这种急性神经病变中未被选择性累及。在每种情况下，传导阻滞和减慢的定位均在螺旋沟处。该方法提供了一种相对简单的方式来评估轴突损失和传导阻滞的大致作用，并且与这些病例早期通常完全的临床恢复情况非常吻合。
