膳食硒缺乏对大鼠胃肠道抗氧化酶系统的影响。
The effect of dietary selenium deficiency on the antioxidant enzyme system in the gastrointestinal tract of the rat.
作者信息
Szymanska E, Siegers C P
机构信息
Institute of Mother and Child, Department of Biochemistry, Warsawa, Poland.
出版信息
Res Commun Chem Pathol Pharmacol. 1992 Mar;75(3):341-6.
PMID:1324517
Abstract
The effect of selenium deficiency on the glutathione content and antioxidant enzymes in the gastrointestinal mucosa was studied. It was found that under Se-deficiency the level of glutathione increased, whereas the activity of Se-dependent glutathione peroxidase decreased. The activities of catalase and glutathione-S-transferase were unaffected. Malondialdehyde content was markedly increased in the glandular stomach of Se-deficient rats.
摘要
研究了硒缺乏对胃肠道黏膜中谷胱甘肽含量和抗氧化酶的影响。结果发现，在缺硒情况下，谷胱甘肽水平升高，而硒依赖性谷胱甘肽过氧化物酶的活性降低。过氧化氢酶和谷胱甘肽-S-转移酶的活性未受影响。缺硒大鼠腺胃中的丙二醛含量显著增加。
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