Suppr超能文献

[单纯主动脉瓣置换术的结果]

[Results of isolated aortic valve replacement].

作者信息

Mikaeloff P h, Perrin A, Delarbre J F, Biron A, Maucort P

出版信息

Nouv Presse Med. 1976 May 22;5(21):1341-5.

PMID:132636
Abstract

Progress in surgical technique and decreased early and late postoperative risk should lead to a modification in the indications for aortic valve replacement, before irreversible myocardial changes have definitively compromised the result of surgery. One hundred and seventy aortic valve replacements (100 pure or predominant aortic stenoses, 70 cases of aortic insufficiency) were carried out by the same surgeon over a period of 4 years with a minimum follow-up of one year and average of 25.4 months, using à Bjork prosthesis or a homograft. Early postoperative mortality was 5.3%, not differing from that associated with other types of valve replacement (mitral, polyvalvular). It is related more directly to surgical technique than to preoperative prognostic factors. Late mortality was 8.1%. Almost one third of these late deaths were related to the surgical technique or to the model of aortic prosthesis used. Stage IV cardiac failure plays a pejorative role in this late mortality, whilst no prognostic role could be demonstrated with respect to angina, meancardiac surface, Sokolow index, mean pulmonary artery pressure or diastolic pressure in the left ventricule. One year after surgery there was found to be a significantly important decrease in the Sokolow index and a modest decrease in mean radiological cardiac surface area. Beyond one year, no further improvement was seen. The majority of the patients surviving surgery had a good functional result since only 1% of the aortic stenosis patients and 7% of the aortic insufficiency group remained in stage III or IV cardiac failure. 78% of the patients who were working before operation were able to resume their professional activity after an average period of 6.2 months. However only 40% of the patients with stage IV failure who underwent surgery could return to work.

摘要

手术技术的进步以及术后早期和晚期风险的降低,应促使在不可逆的心肌改变明确损害手术结果之前,对主动脉瓣置换术的适应症进行调整。在4年的时间里,同一位外科医生进行了170例主动脉瓣置换术(100例单纯或主要为主动脉瓣狭窄,70例主动脉瓣关闭不全),随访时间至少1年,平均为25.4个月,使用比约克人工瓣膜或同种异体移植物。术后早期死亡率为5.3%,与其他类型的瓣膜置换术(二尖瓣、多瓣膜)相关的死亡率无差异。它与手术技术的关系比与术前预后因素的关系更直接。晚期死亡率为8.1%。这些晚期死亡中近三分之一与手术技术或所使用的主动脉人工瓣膜模型有关。IV期心力衰竭在这种晚期死亡率中起不良作用,而对于心绞痛、平均心脏表面积、索科洛夫指数、平均肺动脉压或左心室舒张压,未发现有预后作用。术后1年,索科洛夫指数显著下降,平均放射学心脏表面积略有下降。超过1年,未见进一步改善。大多数手术存活患者功能结果良好,因为只有1%的主动脉瓣狭窄患者和7%的主动脉瓣关闭不全组患者仍处于III期或IV期心力衰竭。78%术前工作的患者在平均6.2个月后能够恢复职业活动。然而,接受手术的IV期心力衰竭患者中只有40%能够重返工作岗位。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验