Gandevia S C
Respir Physiol. 1976 Apr;26(2):163-71. doi: 10.1016/0034-5687(76)90094-3.
Vibration of 100 Hz was delivered longitudinally onto the sternum of anaesthetized cats and rabbits. Vibration consistently reduced the tidal volume by 10-15% without altering the end-expiratory point, and occasionally reduced the respiratory rate. Vibration applied during inspiration reduced the tidal volume as much as if delivered over several breaths. Expiratory vibration did not alter the course of the expiration, nor the volume of the following inspiration. The inhibition of inspiration was unaffected by deafferentation of chest wall skin, bilateral vagotomy, bilateral division of the phrenic nerves and low thoracic spinal transection. Spinal transection above the thoracic cord (C8/T1) abolished usual responses to vibration. The receptors for this reflex probably lie in the chest wall. Vibration inhibited the development of alae nasi tension during inspiration indicating that supraspinal reflex loops were involved. A role for intercostal muscle spindles is suggested.
将100赫兹的振动纵向施加于麻醉猫和兔子的胸骨上。振动持续使潮气量减少10 - 15%，而不改变呼气末点，偶尔也会降低呼吸频率。吸气时施加的振动使潮气量减少的程度与在几次呼吸中施加时相同。呼气时的振动既不改变呼气过程，也不改变随后吸气的量。胸壁皮肤去传入神经、双侧迷走神经切断术、双侧膈神经切断术和胸段低位脊髓横断术均不影响对吸气的抑制作用。胸段脊髓以上（C8/T1）的脊髓横断术消除了对振动的通常反应。这种反射的感受器可能位于胸壁。振动抑制了吸气过程中鼻翼张力的发展，表明涉及脊髓以上的反射环路。提示肋间肌梭可能起作用。
