Nakashima Y, Sueishi K, Morishita Y
First Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka.
Fukuoka Igaku Zasshi. 1992 Aug;83(8):333-7.
We reported a case of mixed tumor arising in the vagina of a 32-year-old Japanese woman. The tumor was a finger-like polyp protruded from the lower portion of the vagina. The histologic feature of the tumor resembled that of pleomorphic adenoma of the salivary gland, consisting of stromal-type cells embedded in the myxomatous stroma, although there was no cartilagenous component. Immunohistochemical study also suggested resemblance to pleomorphic adenoma of salivary gland, being positively stained with antibodies against cytokeratin, epithelial membrane antigen, vimentin and muscle actin, but negatively with an antibody against S-100 protein. The histogenesis of the tumor is not clear, but it may be originated from myoepithelial cells.
我们报告了一例发生在一名32岁日本女性阴道的混合瘤病例。肿瘤为指状息肉，从阴道下部突出。肿瘤的组织学特征类似于唾液腺多形性腺瘤，由嵌入黏液样基质中的间质型细胞组成，尽管没有软骨成分。免疫组织化学研究也提示与唾液腺多形性腺瘤相似，细胞角蛋白、上皮膜抗原、波形蛋白和肌动蛋白抗体呈阳性染色，但S-100蛋白抗体呈阴性染色。肿瘤的组织发生尚不清楚，但可能起源于肌上皮细胞。
