[乙酰胆碱和γ-氨基丁酸对大鼠大脑皮层切片活性钾摄取的辐射后效应]
[The postradiation effect of acetylcholine and GABA on the active potassium uptake by slices of rat cerebral cortex].
作者信息
Dvoretskiĭ A I, Anan'eva T V
出版信息
Radiobiologiia. 1992 Jul-Aug;32(4):540-5.
PMID:1329137
Abstract
Whole-body X irradiation (0.155 and 0.310 C/kg) was shown to modify the biphase effect of acetylcholine and GABA on antigradient K+ uptake by rat brain sections. Radiation made the effects of neuromediators on active K+ transport be differently directed: acetylcholine enhanced the inhibitory effect of radiation and GABA restored the Na-K-pump function.
摘要
全身X射线照射（0.155和0.310库仑/千克）被证明可改变乙酰胆碱和γ-氨基丁酸对大鼠脑切片逆梯度钾摄取的双相效应。辐射使神经介质对活性钾转运的影响呈现不同方向：乙酰胆碱增强了辐射的抑制作用，而γ-氨基丁酸恢复了钠钾泵的功能。
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