Harms B A, Andersen A B, Starling J R
Department of Surgery, University of Wisconsin, Madison.
Surgery. 1992 Oct;112(4):638-46; discussion 646-8.
This report examines the viability of the W reservoir as a reliable option for the treatment of ulcerative colitis and familial polyposis and studies W reservoir adaptation as reflected by changes in compliance and stool frequency.
Since 1984, 109 patients have undergone proctocolectomy with W reservoir reconstruction. Ileal reservoir static compliance was measured in 70 and 57 patients at 2 and 12 months after ileostomy takedown and in 25 patients at 3 years. Compliance was calculated as the change in volume over change in pressure.
Twenty-four-hour stool frequency decreased from 7.3 +/- 0.2 at 2 months to 4.9 +/- 0.2 at 1 year for patients with ulcerative colitis and from 6.3 +/- 0.4 to 3.4 +/- 0.4 for patients with familial polyposis (p less than or equal to 0.05). Compliance increased from 12.7 +/- 0.6 ml/mm Hg to 14.3 +/- 0.6 ml/mm Hg between 2 months and 1 year. No significant increase in compliance occurred after 1 year. Ninety-six percent of patients were continent during the day at 12 months although 10% experienced occasional minor leakage at night. Average postoperative morbidity (for example, small-bowel obstruction, anastomotic complications) was 35%. No operative deaths, pelvic sepsis, or reservoir loss occurred.
We conclude that W ileal reservoirs (1) are an excellent option for ileal reservoir reconstruction, (2) have optimal functional and compliance properties versus lower capacity designs and straight ileoanal pull-through procedures, and (3) maintain stable compliance characteristics and functional reservoir volume after the initial year of adaptation.
本报告探讨了W贮袋作为治疗溃疡性结肠炎和家族性息肉病的可靠选择的可行性,并通过顺应性和排便频率的变化研究W贮袋的适应性。
自1984年以来,109例患者接受了直肠结肠切除并进行W贮袋重建。在回肠造口关闭后2个月和12个月时测量了70例和57例患者的回肠贮袋静态顺应性,在3年时测量了25例患者的回肠贮袋静态顺应性。顺应性计算为容积变化除以压力变化。
溃疡性结肠炎患者的24小时排便频率从2个月时的7.3±0.2次降至1年时的4.9±0.2次,家族性息肉病患者的排便频率从6.3±0.4次降至3.4±0.4次(p≤0.05)。顺应性在2个月至1年之间从12.7±0.6ml/mm Hg增加到14.3±0.6ml/mm Hg。1年后顺应性没有显著增加。96%的患者在12个月时白天能保持控便,尽管10%的患者夜间偶尔有少量渗漏。术后平均发病率(如小肠梗阻、吻合口并发症)为35%。未发生手术死亡、盆腔感染或贮袋丢失。
我们得出结论,W回肠贮袋(1)是回肠贮袋重建的极佳选择;(2)与容量较小的设计和直乙状结肠肛管拖出术相比,具有最佳的功能和顺应性;(3)在适应的第一年之后,能保持稳定的顺应性特征和功能性贮袋容量。