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B组轮状病毒(IDIR株)基因组片段间的末端序列保守性。

Terminal sequence conservation among the genomic segments of a group B rotavirus (IDIR strain).

作者信息

Eiden J J, Vonderfecht S, Petric M

机构信息

Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

出版信息

Virology. 1992 Nov;191(1):495-7. doi: 10.1016/0042-6822(92)90218-e.

DOI:10.1016/0042-6822(92)90218-e
PMID:1329334
Abstract

Terminal nucleic acid sequences were determined for all 11 segments of the IDIR strain of group B rotavirus. Consensus sequences were defined at both ends of the (+) RNA strands as 5' GGN(A/U)NA(A/U)(A/U)(A/U)---and---(A/U)NA(A/G)N(A/C)(C/A)CC3 '. The 5' and 3' terminal sequences of the (+) strand IDIR RNA were not complementary to one another. The IDIR terminal sequences and those of group A rotaviruses (GAR) were similar in that each of the (+) strands began with "GG" and ended with "CC." Otherwise, the IDIR terminal sequences did not match the consensus sequences that have been reported for the ends of the GAR genomic segments.

摘要

测定了B组轮状病毒IDIR株所有11个基因片段的末端核酸序列。(+)RNA链两端的共有序列定义为5' GGN(A/U)NA(A/U)(A/U)(A/U)---和---(A/U)NA(A/G)N(A/C)(C/A)CC3 '。IDIR(+)链RNA的5'和3'末端序列彼此不互补。IDIR末端序列与A组轮状病毒(GAR)的末端序列相似之处在于,每条(+)链均以“GG”开头,以“CC”结尾。否则,IDIR末端序列与已报道的GAR基因组片段末端的共有序列不匹配。

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