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备解素-补体系统的定量研究。

Quantitative studies on the properdin-complement system.

作者信息

LEON M A

出版信息

J Exp Med. 1956 Mar 1;103(3):285-93. doi: 10.1084/jem.103.3.285.

Abstract

Quantitative methods have been developed for the estimation of C'3 and properdin. With these methods, the kinetics of the over-all reaction between properdin, zymosan, and C'3 were investigated. The reaction followed first order kinetics, provided zymosan was in excess, and the serum not diluted beyond 1/4. The reaction rate was proportional to the temperature, and an activation energy of 20,500 calories/mole was found. The distinction between total properdin and available serum properdin is discussed.

摘要

已经开发出定量方法来估算补体C3和备解素。运用这些方法,对备解素、酵母聚糖和补体C3之间的整体反应动力学进行了研究。如果酵母聚糖过量且血清稀释不超过1/4,则该反应遵循一级动力学。反应速率与温度成正比,并且发现其活化能为20,500卡/摩尔。文中还讨论了总备解素和血清中可利用备解素之间的区别。

相似文献

1
Quantitative studies on the properdin-complement system.备解素-补体系统的定量研究。
J Exp Med. 1956 Mar 1;103(3):285-93. doi: 10.1084/jem.103.3.285.
4
Breakdown products of C 3 in human synovial fluids.人体滑液中C3的分解产物。
J Clin Invest. 1969 Aug;48(8):1532-42. doi: 10.1172/JCI106119.

引用本文的文献

1
NEUTRALIZATION OF BACTERIOPHAGE BY THE PROPERDIN SYSTEM.备解素系统对噬菌体的中和作用
Proc Natl Acad Sci U S A. 1956 Jul;42(7):391-4. doi: 10.1073/pnas.42.7.391.
5
[The properdin problem].[备解素问题]
Blut. 1958 Nov;4(5):280-90. doi: 10.1007/BF01630325.
7
[Determination of properdin and complement factors].[备解素与补体因子的测定]
Klin Wochenschr. 1958 Feb 1;36(3):100-7. doi: 10.1007/BF01500450.

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