SKEGGS L T, KAHN J R, SHUMWAY N P
J Exp Med. 1956 Mar 1;103(3):301-7. doi: 10.1084/jem.103.3.301.
The enzymatic conversion of hypertensin I to hypertensin II is described together with the subsequent purification of the product by means of counter-current distribution. Improved methods are also presented for the preparation of renin and its substrate, as well as in methods for the reaction of these materials and the purification of the resulting hypertensin I.
文中描述了血管紧张素I向血管紧张素II的酶促转化过程,以及随后通过逆流分配法对产物进行纯化的方法。还介绍了制备肾素及其底物的改进方法,以及这些物质的反应方法和所得血管紧张素I的纯化方法。