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髓内可生物降解自增强聚乙醇酸植入物对管状骨的影响。对生长中的犬类的实验研究。

The effect of an intramedullary biodegradable self-reinforced polyglycolic acid implant on tubular bone. An experimental study on growing dogs.

作者信息

Miettinen H, Mäkelä E A, Vainio J, Rokkanen P, Törmälä P

机构信息

Department of Surgery, Kuopio University Hospital, Finland.

出版信息

J Biomater Sci Polym Ed. 1992;3(6):435-42. doi: 10.1163/156856292x00411.

Abstract

The purpose of this study was to examine the effects of intramedullary self-reinforced polyglycolic acid (SR-PGA) implant to the femoral bone growth in a growing dog by using radiographic, microradiographic, oxytetracycline-fluorescence, histological, polariscopical and histomorphometric studies. Intramedullary reaming and SR-PGA implant did not cause any longitudinal overgrowth phenomenon, but resulted in a slight increase in femoral neck-angle. The bone histology showed normal features and blood cell counts were within normal limits.

摘要

本研究的目的是通过放射学、显微放射学、土霉素荧光、组织学、偏光显微镜及组织形态计量学研究,检测髓内自增强聚乙醇酸(SR-PGA)植入物对生长犬股骨生长的影响。髓内扩髓及SR-PGA植入未引起任何纵向过度生长现象,但导致股骨颈角度略有增加。骨组织学显示正常特征,血细胞计数在正常范围内。

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