Flam F, Rutqvist L E
Department of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden.
Eur J Epidemiol. 1992 Sep;8(5):683-6. doi: 10.1007/BF00145384.
The paper presents a study of completeness of registration of hydatidiform mole and gestational trophoblastic neoplasia in the Swedish Cancer Registry. The study is based on patients treated in Stockholm County, Sweden from 1971 through 1986. Non-notified cases were identified through a computerized register covering nearly all hospital admissions in the region and local hospital patient register. The results show that 25% of the cases with a diagnosis of hydatidiform mole were not included in the cancer register. Of all patients treated for trophoblastic malignancy, 66% were not recorded in the Cancer Registry. The frequent absence of histopathological confirmation in cases with malignant trophoblastic disease was probably the main factor contributing to the observed under-registration. The study indicates that the Swedish Cancer Registry alone does not provide sufficient data for studies on the incidence of gestational trophoblastic disease.
本文介绍了瑞典癌症登记处对葡萄胎和妊娠滋养细胞肿瘤登记完整性的一项研究。该研究基于1971年至1986年在瑞典斯德哥尔摩县接受治疗的患者。通过一个涵盖该地区几乎所有医院入院情况的计算机化登记册和当地医院患者登记册来识别未报告的病例。结果显示，诊断为葡萄胎的病例中有25%未被纳入癌症登记处。在所有接受滋养细胞恶性肿瘤治疗的患者中，66%未记录在癌症登记处。恶性滋养细胞疾病病例中组织病理学确认的频繁缺失可能是导致观察到登记不足的主要因素。该研究表明，仅瑞典癌症登记处并不为妊娠滋养细胞疾病发病率研究提供足够的数据。
