Swash M, Fox K P
J Neurol Sci. 1976 Sep;29(1):17-32. doi: 10.1016/0022-510x(76)90077-0.
Muscle spindles have been studied in 7 autopsied cases of Duchenne muscular dystrophy. The autopsies of 2 boys of similar age who died without known neuromuscular disease were used as controls. The abnormalities found consisted of degenerative changes, atrophy and loss of intrafusal muscle fibres, thickening of the spindle capsule and widening of the periaxial space. In some very severely affected muscles there was evidence that spindles were destroyed in the course of the disease. Statistical comparison of these observations was made between the pathological and normal material. The muscle spindle innervation appeared normal in sectioned material. Teased preparations were not available for study.
对7例杜兴氏肌营养不良症尸检病例的肌梭进行了研究。选取2名年龄相仿、死因不明且无神经肌肉疾病的男孩的尸检作为对照。发现的异常包括退行性改变、梭内肌纤维萎缩和丧失、梭囊增厚以及轴周间隙增宽。在一些受影响非常严重的肌肉中，有证据表明肌梭在疾病过程中被破坏。对这些观察结果在病理材料和正常材料之间进行了统计学比较。切片材料中的肌梭神经支配看起来正常。无法获得用于研究的 teased 标本。 （注：“teased preparations”可能是指某种特殊的标本制备方法，直译为“ teased 标本”，具体含义需结合专业知识进一步明确）
