[细胞内调节系统在缺氧时大脑皮质神经元活动恢复机制中的作用]
[The involvement of intracellular regulatory systems in the mechanisms of the recovery of the neuronal activity of the cerebral cortex in anoxia].
作者信息
Samoĭlov M O, Semenov D G, Tiul'kova E I, Bolekhan E A
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1992 Jun;78(6):11-7.
PMID:1332889
Abstract
Changes in the membrane-bound calcium (Ca(b)), polyphosphoinositides (PPI) and cAMP, as well as unit spike activity of the cat brain cortex were studied during 30 min of recovery after 5-min anoxia. The cats with poor recovery revealed low Ca(b) and PPI but high level of the cAMP content. The group of cats with more successful restitution after anoxia revealed a sharp increase in the Ca(b) and PPI and not in the cAMP.
摘要
在5分钟缺氧后的30分钟恢复过程中，研究了猫脑皮层中膜结合钙（Ca(b)）、多磷酸肌醇（PPI）和环磷酸腺苷（cAMP）的变化以及单位峰活动。恢复较差的猫显示Ca(b)和PPI水平较低，但cAMP含量较高。缺氧后恢复较好的一组猫显示Ca(b)和PPI急剧增加，而cAMP没有增加。
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