Malý J, Schück O
Physiol Bohemoslov. 1976;25(3):213-6.
The effect of two days' KC1 administration per os (total amount 11 g, i.e. 140 mEq potassium) on renal uric acid excretion was studied in healthy subjects under conditions of water diuresis. A significant increase in the uric acid excretory fraction (CUA/CCr..100) was found, from 8.04% in the control test to 10.31% under experimental conditions. Elevated renal uric excretion led to a significant drop in the plasma uric acid level from 4.9 mg% to 4.2 mg% after the administration to KC1. The findings suggest that KC1 influences the tubular transport of uric acid, but the mechanism of its action is still obscure.
在水利尿条件下，对健康受试者口服氯化钾两天（总量11克，即140毫当量钾）对肾脏尿酸排泄的影响进行了研究。发现尿酸排泄分数（CUA/CCr..100）显著增加，从对照试验中的8.04%增至实验条件下的10.31%。肾脏尿酸排泄增加导致口服氯化钾后血浆尿酸水平从4.9毫克%显著降至4.2毫克%。这些发现表明氯化钾影响尿酸的肾小管转运，但其作用机制仍不清楚。
