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年龄和饥饿对大鼠血氧分压、二氧化碳分压及血细胞比容值的影响。

Influence of age and starvation on pO2, pCO2 and haematocrit values in the rat.

作者信息

Mourek J

出版信息

Physiol Bohemoslov. 1976;25(3):245-50.

PMID:133366
Abstract

The author determined the effect of acute starvation on the arterial pO2 and pCO2 value (analysed on a micro-Astrup apparatus) in rats of different ages; in infant rats, this was done by separating them from the female and the nest for 24 hours. Arterial blood was obtained by incising the tail artery. It was found that the pO2 value in rat arterial blood rose signficantly during ontogenesis. At 10 and 14 days the mean pO2 value was 68 torr, while at 25 days and in adult rats it was 92-95 torr. No marked changes were found in CO2 during ontogenesis (the mild drop was not statistically significant). In 10- and 14-day-old rats, 24 hours' starvation caused a significant decrease in pO2. In older rats, deprivation of food and water did not significantly affect the pO2; in the arterial blood. The arterial blood pCO2 was not influenced by starvation. The development of the haematocrit values in mixed blood (obtained by decapitation) during ontogenesis was in agreement with findings in the literature, i.e. a drors' complete starvation produced no change in the haematocrit values in 5- and 10-day-old rats, but a marked increase was recorded in older rats.

摘要

作者测定了急性饥饿对不同年龄大鼠动脉血氧分压(pO₂)和二氧化碳分压(pCO₂)值(使用微量阿斯特鲁普仪器分析)的影响;对于幼鼠,通过将它们与母鼠和巢穴分离24小时来实现。通过切开尾动脉获取动脉血。研究发现,大鼠动脉血中的pO₂值在个体发育过程中显著升高。在10日龄和14日龄时,平均pO₂值为68托,而在25日龄和成年大鼠中,该值为92 - 95托。在个体发育过程中未发现二氧化碳有明显变化(轻微下降无统计学意义)。在10日龄和14日龄的大鼠中,24小时饥饿导致pO₂显著降低。在年龄较大的大鼠中,禁食禁水对动脉血中的pO₂没有显著影响。动脉血pCO₂不受饥饿影响。个体发育过程中混合血(通过断头获取)的血细胞比容值变化与文献中的发现一致,即完全饥饿对5日龄和10日龄大鼠的血细胞比容值没有影响,但在年龄较大的大鼠中记录到显著增加。

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