兔出血性疾病病毒抗原的免疫组织化学定位
Immunohistochemical localization of the rabbit haemorrhagic disease viral antigen.
作者信息
Alexandrov M, Peshev R, Yanchev I, Bozhkov S, Doumanova L, Dimitrov T, Zacharieva S
机构信息
Institute of General and Comparative Pathology, Bulgarian Academy of Science, Sofia.
出版信息
Arch Virol. 1992;127(1-4):355-63. doi: 10.1007/BF01309598.
Immunohistochemical investigations were carried out to determine organ and cellular localization of the rabbit haemorrhagic disease viral antigen (RHDVA). It was found in certain parenchymal liver cells near the interlobular septs and in some macrophages and pseudoeosinophils of all studied organs and blood. Whereas in morphologically preserved hepatocytes and macrophages the RHDVA accumulated in the nuclei, in cells with disintegrated nuclei it was distributed throughout the cytoplasm.
进行免疫组织化学研究以确定兔出血性疾病病毒抗原（RHDVA）的器官和细胞定位。在小叶间隔附近的某些肝实质细胞以及所有研究器官和血液中的一些巨噬细胞和假嗜酸性粒细胞中发现了该抗原。在形态学上保存完好的肝细胞和巨噬细胞中，RHDVA积聚在细胞核中，而在细胞核解体的细胞中，它分布于整个细胞质中。
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