Cludts I, Droogmans L, Cleuter Y, Kettmann R, Burny A
Laboratoire de Chimie Biologique, Université Libre de Bruxelles, Rhode-St-Genèse, Belgium.
DNA Seq. 1992;3(1):55-9. doi: 10.3109/10425179209039696.
We report the cloning and the sequencing of a cDNA coding for the mature bovine interleukin 7 (IL-7). The clone was isolated from a bovine leukemia virus (BLV)-induced B cell-lymphosarcoma cDNA library. The 5' non-coding sequence and the sequence of the signal peptide were obtained from a clone isolated from a bovine genomic library. The entire bovine IL-7 protein is 176 amino acids long and shows 75 and 65% homology to published sequences of human and murine IL-7, respectively.
我们报告了编码成熟牛白细胞介素7（IL-7）的cDNA的克隆及测序。该克隆是从牛白血病病毒（BLV）诱导的B细胞淋巴瘤cDNA文库中分离得到的。5'非编码序列和信号肽序列是从牛基因组文库中分离得到的一个克隆中获得的。完整的牛IL-7蛋白由176个氨基酸组成，与已发表的人及小鼠IL-7序列分别具有75%和65%的同源性。
