Foggie A, Jones G E, Buxton D
Res Vet Sci. 1976 Jul;21(1):28-35.
Six colostrum-deprived SPF lambs inoculated endobronchially with a second passage broth culture of a Scottish strain of Mycoplasma ovipneumoniae, were killed in batches of two at seven, 14 and 28 days post-inoculation. One lamb from each batch showed macroscopic and microscopic lung lesions similar to but milder than those described for respiratory mycoplasmoses in other species of animals and exhibited minor clinical symptoms. Mycoplasma were recovered from all infected but from no control animals: five infected lambs yielded mycoplasma from lung tissue. Two lambs infected with M ovipneumoniae by endobronchial intubation were placed in contact with six other SPF lambs. M ovipneumoniae was recovered from the upper respiratory tract only of all six contact lambs, but no pathological changes were noted in their lungs. Both donor lambs yielded mycoplasma from lung tissue, but microscopic lesions were detected in only one of them, and these were minimal. No seroconversion due to the infection could be demonstrated in any of the lambs by either the indirect haemagglutination or metabolic inhibition tests.
六只初乳缺乏的无特定病原体（SPF）羔羊经支气管内接种了一株苏格兰绵羊肺炎支原体菌株的第二代肉汤培养物，在接种后第7天、14天和28天，每次两只分批处死。每批中的一只羔羊表现出肉眼和显微镜下的肺部病变，与其他动物种类的呼吸道支原体病所描述的病变相似但较轻，并表现出轻微的临床症状。支原体从所有感染动物中分离出来，但未从对照动物中分离出来：五只感染羔羊的肺组织中分离出支原体。通过支气管内插管感染绵羊肺炎支原体的两只羔羊与另外六只SPF羔羊接触。仅在所有六只接触羔羊的上呼吸道中分离出绵羊肺炎支原体，但在它们的肺部未发现病理变化。两只供体羔羊的肺组织中分离出支原体，但仅在其中一只中检测到显微镜下病变，且病变轻微。通过间接血凝试验或代谢抑制试验，在任何一只羔羊中均未证明因感染而发生血清转化。
