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极高频低强度电磁辐射对人自然杀伤细胞细胞毒性活性的影响

[The effect of electromagnetic radiation with extremely high frequency and low intensity on cytotoxic activity of human natural killer cells].

作者信息

Fedorchuk A G, Skivka L M, Stoliarov Z E, Levchuk Iu N, Mostovaia A V

出版信息

Biofizika. 1992 Sep-Oct;37(5):957-62.

PMID:1335293
Abstract

EHF electromagnetic radiation under short-time action suppresses the cytotoxical activity of the natural killer cells from granulocyte fraction and peripheral blood of healthy volunteers; the observed effect is non-linear. Under the long-time irradiation of the natural killer cells from the mononuclear fraction of blood, the suppressing effect gets a practically linear character after the 20-30 minutes action. Under the long-time irradiation of peripheral blood the insignificant stimulation of natural killers was observed. It is assumed that the radiation applied can suppress the cytotoxic activity of the natural killers, breaking the normal metabolic pathway of phosphatidylinositphosphate.

摘要

短时间作用下的高频电磁场辐射会抑制健康志愿者粒细胞组分和外周血中自然杀伤细胞的细胞毒性活性;观察到的效应是非线性的。在对血液单核细胞组分中的自然杀伤细胞进行长时间照射时,在作用20 - 30分钟后,抑制效应呈现出近乎线性的特征。在外周血长时间照射下,观察到自然杀伤细胞有轻微的刺激作用。据推测,所施加的辐射会抑制自然杀伤细胞的细胞毒性活性,破坏磷脂酰肌醇磷酸的正常代谢途径。

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