Slivinskiĭ G G, Krifuks O I, Magda I N
Radiobiologiia. 1989 Jul-Aug;29(4):564-6.
A study was made of sensitivity of NKLy tumor fractions, differing in the proliferative activity, position in the cell cycle, and ploidy, to membrane-toxic action of natural killer cells from mouse spleen. The membrane toxicity index for cells of three out of five fractions under study was shown to decrease after exposure to 4 Gy radiation. It is concluded that there is no correlation between NKLy cell sensitivity to membrane-toxic effect of natural killer cells and their radiosensitivity as well as their ability to repair potentially lethal damages.
对NKLy肿瘤细胞组分进行了研究，这些组分在增殖活性、细胞周期位置和倍性方面存在差异，研究其对来自小鼠脾脏的自然杀伤细胞的膜毒性作用的敏感性。研究的五个组分中有三个组分的细胞在受到4 Gy辐射后，其膜毒性指数降低。得出的结论是，NKLy细胞对自然杀伤细胞的膜毒性作用的敏感性与其放射敏感性以及修复潜在致死性损伤的能力之间没有相关性。
