Keenan M J, Hegsted M, Wozniak P J, Bott J D, Reisenauer A
School of Human Ecology, Louisiana State University Agricultural Center, Baton Rouge 70803.
Int J Vitam Nutr Res. 1992;62(3):228-32.
Weanling rats (21 days old) from either a low vitamin D colony or an adequate vitamin D colony fed either a vitamin D adequate or a vitamin D deprived AIN-76A purified diet were used as a model to investigate interactions of vitamin D status with dietary sodium zeolite A (100 mg/kg body wt/day). Rats with adequate or replete vitamin D status had greater overall body weight gain, dry tibia weights and femur densities and ash weights than rats fed a vitamin D deprived diet. Addition of sodium zeolite A to the diets did not have an effect on plasma calcium, body weight gain or on femur density, ash and percent ash. Dietary sodium zeolite A increased total tibia fat in rats fed the vitamin D adequate diet and decreased total tibia fat in rats fed the vitamin D deprived diet. This effect of sodium zeolite A appeared to be beneficial to bone status in the groups fed adequate vitamin D, since these treatment groups had higher, although not significant, dry tibia weights with and without fat.
选用来自低维生素D群体或充足维生素D群体的21日龄断奶大鼠，给它们喂食维生素D充足或缺乏维生素D的AIN - 76A纯化日粮，以此作为模型来研究维生素D状态与日粮中沸石A钠（100毫克/千克体重/天）之间的相互作用。维生素D状态充足或充足的大鼠比喂食缺乏维生素D日粮的大鼠总体体重增加更多、胫骨干重、股骨密度和骨灰重量更高。在日粮中添加沸石A钠对血浆钙、体重增加或股骨密度、骨灰及骨灰百分比没有影响。日粮中的沸石A钠增加了喂食维生素D充足日粮大鼠的胫骨总脂肪，并降低了喂食缺乏维生素D日粮大鼠的胫骨总脂肪。沸石A钠的这种作用似乎对喂食充足维生素D的组别的骨骼状态有益，因为这些处理组无论有无脂肪，胫骨干重都较高，尽管不显著。
