• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Protein phosphatase X has been highly conserved during mammalian evolution.

作者信息

Brewis N D, Cohen P T

机构信息

Department of Biochemistry, University, Dundee, UK.

出版信息

Biochim Biophys Acta. 1992 Dec 29;1171(2):231-3. doi: 10.1016/0167-4781(92)90129-n.

DOI:10.1016/0167-4781(92)90129-n
PMID:1336397
Abstract

Complementary DNA encoding human protein phosphatase X (PPX, also designated PPP4 in the human genome nomenclature) was isolated from a teratocarcinoma library. The deduced amino acid sequence of human PPX differs from that of rabbit PPX in only two in 307 amino acids, demonstrating that the structure of PPX has been highly conserved during the course of mammalian evolution.

摘要

相似文献

1
Protein phosphatase X has been highly conserved during mammalian evolution.
Biochim Biophys Acta. 1992 Dec 29;1171(2):231-3. doi: 10.1016/0167-4781(92)90129-n.
2
Identification of a third alternatively spliced cDNA encoding the catalytic subunit of protein phosphatase 2B beta.
Biochim Biophys Acta. 1991 Feb 16;1088(2):308-10. doi: 10.1016/0167-4781(91)90069-x.
3
PPX, a novel protein serine/threonine phosphatase localized to centrosomes.PPX是一种定位于中心体的新型蛋白丝氨酸/苏氨酸磷酸酶。
EMBO J. 1993 Mar;12(3):987-96. doi: 10.1002/j.1460-2075.1993.tb05739.x.
4
Identification and molecular cloning of two homologues of protein phosphatase X from Arabidopsis thaliana.拟南芥中蛋白磷酸酶X的两个同源物的鉴定与分子克隆。
Plant Mol Biol. 1993 Dec;23(6):1177-85. doi: 10.1007/BF00042351.
5
Protein serine/threonine phosphatases; an expanding family.
FEBS Lett. 1990 Aug 1;268(2):355-9. doi: 10.1016/0014-5793(90)81285-v.
6
Cloning of protein-serine/threonine phosphatases.
Methods Enzymol. 1991;201:398-408. doi: 10.1016/0076-6879(91)01036-2.
7
Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparative analysis of amino acid sequences.
Biochim Biophys Acta. 1992 Feb 28;1130(1):100-4. doi: 10.1016/0167-4781(92)90471-b.
8
PCR cloning of the cDNA of rabbit skeletal muscle protein phosphatase inhibitor-2.兔骨骼肌蛋白磷酸酶抑制剂2 cDNA的PCR克隆
Biochem Biophys Res Commun. 1992 Jul 31;186(2):1168-70. doi: 10.1016/0006-291x(92)90869-m.
9
Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domain.蛋白酪氨酸磷酸酶家族另一成员的鉴定:酪氨酸磷酸酶结构域中选择性剪接的证据。
Proc Natl Acad Sci U S A. 1990 Jun;87(12):4444-8. doi: 10.1073/pnas.87.12.4444.
10
Animal histo-blood group ABO genes.
Biochem Biophys Res Commun. 1992 Nov 30;189(1):154-64. doi: 10.1016/0006-291x(92)91538-2.

引用本文的文献

1
Comprehensive analysis of PPP4C's impact on prognosis, immune microenvironment, and immunotherapy response in lung adenocarcinoma using single-cell sequencing and multi-omics.基于单细胞测序和多组学技术综合分析 PPP4C 对肺腺癌预后、免疫微环境和免疫治疗反应的影响
Front Immunol. 2024 Jul 4;15:1416632. doi: 10.3389/fimmu.2024.1416632. eCollection 2024.
2
The phospho-landscape of the survival of motoneuron protein (SMN) protein: relevance for spinal muscular atrophy (SMA).运动神经元存活蛋白 (SMN) 磷酸化图谱:与脊髓性肌萎缩症 (SMA) 的相关性。
Cell Mol Life Sci. 2022 Aug 25;79(9):497. doi: 10.1007/s00018-022-04522-9.
3
Cell Cycle and DNA Repair Regulation in the Damage Response: Protein Phosphatases Take Over the Reins.
细胞周期和 DNA 修复调控在损伤反应中的作用:蛋白磷酸酶接管缰绳。
Int J Mol Sci. 2020 Jan 10;21(2):446. doi: 10.3390/ijms21020446.
4
Role of protein phosphatases PP1, PP2A, PP4 and Cdc14 in the DNA damage response.蛋白磷酸酶PP1、PP2A、PP4和Cdc14在DNA损伤反应中的作用。
Cell Stress. 2019 Feb 21;3(3):70-85. doi: 10.15698/cst2019.03.178.
5
Protein phosphatase 4 plays dual roles during cell proliferation.蛋白磷酸酶4在细胞增殖过程中发挥双重作用。
Cell Prolif. 2016 Apr;49(2):219-35. doi: 10.1111/cpr.12249. Epub 2016 Apr 3.
6
Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells.蛋白磷酸酶4调节白血病细胞和原代人T细胞中的细胞凋亡。
Leuk Res. 2009 Nov;33(11):1539-51. doi: 10.1016/j.leukres.2009.05.013. Epub 2009 Jun 18.
7
PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.PP4R4/KIAA1622与磷酸蛋白磷酸酶4形成一种新型的稳定胞质复合物。
J Biol Chem. 2008 Oct 24;283(43):29273-84. doi: 10.1074/jbc.M803443200. Epub 2008 Aug 20.
8
Kinetoplastid PPEF phosphatases: dual acylated proteins expressed in the endomembrane system of Leishmania.动质体PPEF磷酸酶:在利什曼原虫内膜系统中表达的双酰化蛋白。
Mol Biochem Parasitol. 2007 Mar;152(1):22-34. doi: 10.1016/j.molbiopara.2006.11.008. Epub 2006 Dec 4.
9
The Arabidopsis thaliana PPX/PP4 phosphatases: molecular cloning and structural organization of the genes and immunolocalization of the proteins to plastids.拟南芥PPX/PP4磷酸酶:基因的分子克隆、结构组织及蛋白质在质体中的免疫定位
Plant Mol Biol. 2000 Nov;44(4):499-511. doi: 10.1023/a:1026587405656.
10
A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres.一种新的50 kDa蛋白与蛋白磷酸酶4形成复合物,并位于中心体微管组织中心。
Biochem J. 2000 May 1;347 Pt 3(Pt 3):845-55.