Eisenstein R, Kuettner K
Atherosclerosis. 1976 Jul-Aug;24(1-2):37-46. doi: 10.1016/0021-9150(76)90062-9.
Electron microscopy of ruthenium red stained bovine aorta before and after chondroitinase digestion demonstrates proteoglycans on and between collagen fibrils. The collagen-associated proteoglycans include a proteoglycan previously purified from this tissue as demonstrated by immunocytochemistry and are extractable with high molar guanidine HC1. In loci rich in proteoglycans such as areas of turbulent flow in calves, more proteoglycan can be demonstrated morphologically, and these molecules also coat elastin.
对经软骨素酶消化前后的钌红染色牛主动脉进行电子显微镜检查，结果表明蛋白聚糖存在于胶原纤维上及纤维之间。通过免疫细胞化学证实，与胶原相关的蛋白聚糖包括一种先前从该组织中纯化出的蛋白聚糖，并且可用高摩尔浓度的盐酸胍提取。在富含蛋白聚糖的部位，如小牛体内血流湍急的区域，从形态学上可显示出更多的蛋白聚糖，并且这些分子也覆盖在弹性蛋白上。
