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原发性人疱疹病毒6型感染中的致命性脑炎/脑病

Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection.

作者信息

Asano Y, Yoshikawa T, Kajita Y, Ogura R, Suga S, Yazaki T, Nakashima T, Yamada A, Kurata T

机构信息

Department of Pediatrics, Fujita Health University School of Medicine, Aichi, Japan.

出版信息

Arch Dis Child. 1992 Dec;67(12):1484-5. doi: 10.1136/adc.67.12.1484.

Abstract

An encephalitic illness with a fatal outcome occurred in a 9 month old girl with virologically confirmed exanthem subitum. Human herpes-virus-6 (HHV-6) DNA was found in the cerebrospinal fluid at the acute stage of the disease by the polymerase chain reaction, but the virus antigen was not detected in her brain tissue. This suggests that HHV-6-induced encephalitis/encephalopathy may be due to a non-infectious process.

摘要

一名9个月大的女童患了具有致命后果的脑炎,其幼儿急疹经病毒学确诊。在疾病急性期,通过聚合酶链反应在脑脊液中发现了人疱疹病毒6型(HHV-6)DNA,但在其脑组织中未检测到病毒抗原。这表明HHV-6诱导的脑炎/脑病可能是由非感染性过程引起的。

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本文引用的文献

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Meningo-encephalitis associated with HHV-6 related exanthem subitum.
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Human herpesvirus 6 (HHV-6) infection in the central nervous system.
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