Pulvirenti L
Department of Neurology, C. Mondino Foundation, Pavia, Italy.
Funct Neurol. 1992 Nov-Dec;7(6):481-90.
The search for the neural determinants of learning and memory has recently focused on phenomena of neural plasticity. The present paper will try to review and relate the functional significance of such specific plastic changes within neural elements to the process of learning in several species and cell types. Pioneer work proposed in simple organisms and recent emerging evidence on the role of the NMDA receptor complex and calcium-related events will be analyzed in the light of experimental findings suggesting that common biochemical events may underlie different forms of experience-dependent neural adaptation.
对学习和记忆的神经决定因素的探索最近聚焦于神经可塑性现象。本文将尝试回顾神经元内这种特定可塑性变化的功能意义，并将其与几种物种和细胞类型的学习过程联系起来。鉴于实验结果表明常见的生化事件可能是不同形式的经验依赖性神经适应的基础，我们将分析在简单生物体中提出的先驱性工作以及最近关于NMDA受体复合物和钙相关事件作用的新证据。
