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1
Metabolism of 4-C14-testosterone in human subjects. I. Distribution in bile, blood, feces and urine.人体中4-C14-睾酮的代谢。I. 在胆汁、血液、粪便和尿液中的分布。
J Clin Invest. 1956 Dec;35(12):1331-9. doi: 10.1172/JCI103389.
2
Fate of long-acting testoster one-ester in rabbit: its distribution in blood, bile, urine and feces.长效睾酮酯在兔体内的代谢命运：其在血液、胆汁、尿液和粪便中的分布。
Endocrinol Jpn. 1957 Sep;4(3):147-54. doi: 10.1507/endocrj1954.4.147.
3
C14-Cholesterol. III. Excretion of carbons 4 and 26 in feces, urine, and bile.碳14标记的胆固醇。III. 碳4和碳26在粪便、尿液及胆汁中的排泄情况
J Biol Chem. 1952 Sep;198(1):93-104.
4
[On the metabolism of 3: 3'-diiodothyronine].
Biochim Biophys Acta. 1956 Mar;19(3):490-6. doi: 10.1016/0006-3002(56)90472-3.
5
METABOLISM OF COPROSTANOL-C14 AND CHOLESTANOL-4-C14 IN MAN.人粪甾烷-C14和胆甾烷-4-C14在人体内的代谢
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6
THE FATE OF TRITIUM-LABELLED BETA-GLYCYRRHETIC ACID IN THE RAT.氚标记的β-甘草次酸在大鼠体内的代谢情况
J Pharm Pharmacol. 1963 Aug;15:500-6. doi: 10.1111/j.2042-7158.1963.tb12825.x.
7
Bile pigments in stool and urine.粪便和尿液中的胆色素。
Manit Med Rev. 1949 Jul;29(7):369.
8
Porphyrin chromogens or precursors in urine, blood, bile, and feces.
J Lab Clin Med. 1951 Jun;37(6):831-42.
9
[MESOBILIFUCHSINS].[中胆色素]
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Composition of the urobilin group in urine bile, and feces and the significance of variations in health and disease.尿液、胆汁和粪便中尿胆素组的组成及其在健康和疾病中的变化意义。
J Lab Clin Med. 1959 Jul;54(1):1-25.

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Estradiol metabolism by gut microbiota in women's depression pathogenesis: inspiration from nature.肠道微生物群在女性抑郁症发病机制中的雌二醇代谢：来自自然的启示
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Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway.肠道细菌通过还原性OsrABC途径代谢天然和合成类固醇激素。
bioRxiv. 2024 Oct 9:2024.10.08.617280. doi: 10.1101/2024.10.08.617280.
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Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut.雄性小鼠肠道中雄激素降解肠道细菌对循环雄激素的调节作用。
Gut Microbes. 2023 Jan-Dec;15(1):2183685. doi: 10.1080/19490976.2023.2183685.
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Long-term high loading intensity of aerobic exercise improves skeletal muscle performance the gut microbiota-testosterone axis.长期高强度有氧运动可改善骨骼肌性能及肠道微生物群-睾酮轴。
Front Microbiol. 2022 Dec 21;13:1049469. doi: 10.3389/fmicb.2022.1049469. eCollection 2022.
5
Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.睾酮的主要葡萄糖醛酸代谢物主要由人肝、肠和肾中的 MRP2 和 MRP3 转运。
J Steroid Biochem Mol Biol. 2019 Jul;191:105350. doi: 10.1016/j.jsbmb.2019.03.027. Epub 2019 Apr 5.
6
Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism.定量描述人肝和肠中的 UDP-葡糖醛酸基转移酶 2B17 及其在睾酮首过代谢中的作用。
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Reexamination of pharmacokinetics of oral testosterone undecanoate in hypogonadal men with a new self-emulsifying formulation.采用新型自乳化制剂对性腺功能减退男性口服十一酸睾酮的药代动力学进行重新研究。
J Androl. 2012 Mar-Apr;33(2):190-201. doi: 10.2164/jandrol.111.013169. Epub 2011 Apr 7.
8
Steroid metabolism in the cat. Biliary and urinary excretion of metabolites of [4-C]testosterone.猫体内的类固醇代谢。[4-C]睾酮代谢产物的胆汁和尿液排泄。
Biochem J. 1965 Mar;94(3):778-82. doi: 10.1042/bj0940778.
9
[Androgens in the peripheral venous blood of healthy pregnant women and of those with late gestoses].[健康孕妇及晚期妊娠中毒症患者外周静脉血中的雄激素]
Klin Wochenschr. 1959 Sep 15;37:966-71. doi: 10.1007/BF01485150.
10
STUDIES ON THE ORIGIN OF TESTOSTERONE IN THE URINE OF NORMAL ADULT SUBJECTS AND PATIENTS WITH VARIOUS ENDOCRINE DISORDERS.正常成年受试者及各种内分泌紊乱患者尿液中睾酮来源的研究。
J Clin Invest. 1964 Jun;43(6):1083-9. doi: 10.1172/JCI104992.

本文引用的文献

1
The isolation of two transformation products of testosterone from urine.从尿液中分离出睾酮的两种转化产物。
Biochem J. 1939 Apr;33(4):559-64. doi: 10.1042/bj0330559.
2
Urinary metabolites after intravenous injection of human subjects with testosterone.对人体受试者静脉注射睾酮后的尿液代谢产物。
J Biol Chem. 1951 Nov;193(1):219-26.
3
The role of the liver and kidneys in the metabolism of intravenous testosterone by human subjects.肝脏和肾脏在人体受试者静脉注射睾酮代谢中的作用。
J Clin Endocrinol Metab. 1951 Sep;11(9):897-912. doi: 10.1210/jcem-11-9-897.
4
Metabolism of testosterone-3-C14 in the guinea pig.豚鼠中睾酮-3-C14的代谢
Endocrinology. 1955 Mar;56(3):267-70. doi: 10.1210/endo-56-3-267.
5
Metabolism of 4-C 14-cortisol in man: body distribution and rates of conjugation.
J Clin Endocrinol Metab. 1956 Sep;16(9):1137-50. doi: 10.1210/jcem-16-9-1137b.
6
The physiological disposition and metabolic fate of hydrocortisone in man.氢化可的松在人体中的生理处置与代谢命运
J Clin Invest. 1955 Dec;34(12):1779-94. doi: 10.1172/JCI103233.
7
The fate of hydrocortisone-4-C14 in man.氢化可的松-4-C14在人体中的代谢情况。
J Clin Invest. 1954 Aug;33(8):1106-15. doi: 10.1172/JCI102984.
8
The fate of testosterone infused intravenously in man.静脉注射睾酮在人体内的代谢情况。
J Biol Chem. 1954 Feb;206(2):863-74.
9
Studies with testosterone-d in normal men.对正常男性使用睾酮 - d 的研究。
J Biol Chem. 1954 Feb;206(2):845-61.
10
Excretion of the metabolites of testosterone-4-C14 in the rat.大鼠体内睾酮 - 4 - C14代谢产物的排泄情况。
J Biol Chem. 1953 Feb;200(2):661-8.

Metabolism of 4-C14-testosterone in human subjects. I. Distribution in bile, blood, feces and urine.

作者信息

SANDBERG A A, SLAUNWHITE W R

出版信息

J Clin Invest. 1956 Dec;35(12):1331-9. doi: 10.1172/JCI103389.

DOI:10.1172/JCI103389
PMID:13385331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC441714/
Abstract
摘要