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Nucleotide sequence of endothelin-1 cDNA from rabbit endothelial cells.

作者信息

Marsden P A, Sultan P, Cybulsky M, Gimbrone M A, Brenner B M, Collins T

机构信息

Department of Medicine, St. Michael's Hospital, Toronto, Canada.

出版信息

Biochim Biophys Acta. 1992 Jan 6;1129(2):249-50. doi: 10.1016/0167-4781(92)90499-p.

DOI:10.1016/0167-4781(92)90499-p
PMID:1339290
Abstract

A cDNA encoding rabbit endothelin-1 (ET-1) was isolated by plaque hybridization from a rabbit inferior vena caval endothelial cell lambda gt11 cDNA library using human ET-1 cDNA as the hybridization probe. DNA sequence analysis indicates that mature 21 amino acid rabbit ET-1 is derived from a 202 amino acid precursor, via a 39 amino acid intermediate 'big' ET-1.

摘要

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