Sawada H, Shibata Y, Shionoya M, Kato K
Cardiovascular Institute, Tokyo.
J Cardiol. 1992;22(2-3):495-501.
Aortic regurgitation (AR) and aortic root dilatation in 29 consecutive patients with bicuspid aortic valves but without aortic root disease (20 males, and 9 females: aged 27-85 years) were studied using two-dimensional echocardiography. The normal ranges of aortic root dimensions were calculated from values of 185 normal subjects, as 95% confidence intervals. AR was observed in 17 patients by color flow mapping. In 12 of the 17 AR patients, no significant lesion of the aortic cusp was detected by two-dimensional echocardiography. These 12 AR patients were compared with 12 patients without AR. Increase in dimension of the aortic root was relatively frequent in the 12 AR patients at the aortic annulus (AA) (67 vs 17%, p < 0.05), and at the sinus of Valsalva (A1) (67 vs 17%, p < 0.05). At the ascending aorta 5 mm distal to the sinus of Valsalva (A2), the difference was not significant (58 vs 17%, p < 0.09). The 12 bicuspid AR patients without significant lesions of the aortic cusp were compared with 41 AR patients with normal tricuspid aortic valves. The frequencies of cases with increased aortic root dimension were 67 vs 46% (ns) at the AA, 67 vs 22% (p < 0.05) at A1 and 58 vs 5% at A2 (p < 0.01). Thus, aortic annular dilatation was thought to be the cause of AR in bicuspid and tricuspid aortic valves without significant lesions of the aortic cusps, and generalized dilatation of the aortic root was more frequent in bicuspid AR patients than in tricuspid AR patients.(ABSTRACT TRUNCATED AT 250 WORDS)
对29例连续的二叶式主动脉瓣患者(无主动脉根部疾病,20例男性,9例女性,年龄27 - 85岁)进行主动脉反流(AR)和主动脉根部扩张的研究,采用二维超声心动图。根据185名正常受试者的值计算主动脉根部尺寸的正常范围,作为95%置信区间。通过彩色血流图在17例患者中观察到AR。在这17例AR患者中的12例中,二维超声心动图未检测到主动脉瓣叶的明显病变。将这12例AR患者与12例无AR的患者进行比较。在12例AR患者中,主动脉根部在主动脉瓣环(AA)处尺寸增加相对频繁(67%对17%,p < 0.05),在主动脉窦(A1)处也是如此(67%对17%,p < 0.05)。在主动脉窦(A2)远端5mm处的升主动脉,差异不显著(58%对17%,p < 0.09)。将12例无主动脉瓣叶明显病变的二叶式AR患者与41例具有正常三叶式主动脉瓣的AR患者进行比较。主动脉根部尺寸增加的病例频率在AA处为67%对46%(无显著性差异),在A1处为67%对22%(p < 0.05),在A2处为58%对5%(p < 0.01)。因此,主动脉瓣环扩张被认为是无主动脉瓣叶明显病变的二叶式和三叶式主动脉瓣中AR的原因,并且二叶式AR患者中主动脉根部的普遍扩张比三叶式AR患者更常见。(摘要截断于250字)