Pandol S J, Rutherford R E
Department of Medicine, Veterans Affairs Hospital, San Diego.
Yale J Biol Med. 1992 Sep-Oct;65(5):399-405; discussion 437-40.
In the past decade, there have been remarkable advances in our understanding of the calcium messenger system that mediates the effects of various agonists. The purpose of the present article is to describe two areas of current interest in the calcium signaling field--quantal calcium release and calcium entry into the cell--using the pancreatic acinar cell as a model. Proposed mechanisms describing these phenomena and the role they play in the kinetics of calcium movements in the cell are discussed.
在过去十年里，我们对介导各种激动剂作用的钙信使系统的理解取得了显著进展。本文旨在以胰腺腺泡细胞为模型，描述钙信号领域当前两个受关注的方面——量子钙释放和钙进入细胞。文中讨论了描述这些现象的推测机制以及它们在细胞钙运动动力学中所起的作用。
