Sigola L B, Adewuyi J O, Mufunda J
Department of Physiology and Haematology, Medical Faculty University of Zimbabwe.
Cent Afr J Med. 1992 Dec;38(12):447-50.
Plasma fibrinogen levels, leucocytes and platelets are among the many factors known to influence haemostasis. Impaired haemostatic processes in hypertension are thought to contribute to the other cardiovascular diseases seen in this condition. This study compares the level of plasma fibrinogen, and leucocyte and platelet counts between 17 male hypertensives and 24 male normotensives. The results for the hypertensives were: leucocyte count mean 5.45 x 10(9)/L, platelet count mean 234.7 x 10(9)/L, and plasma fibrinogen 4.13 g/L. The results for the normotensives were: leucocyte count mean 4.83 x 10(9)/L, platelet count mean 222.9 x 10(9)/L, and plasma fibrinogen 3.27 g/L. The hypertensives had higher plasma fibrinogen levels, and leucocyte and platelet counts compared to the normotensives, but this only reached statistical significance for the plasma fibrinogen levels (p < 0.025).
血浆纤维蛋白原水平、白细胞和血小板是已知影响止血的众多因素之一。高血压患者止血过程受损被认为会导致该疾病中出现的其他心血管疾病。本研究比较了17名男性高血压患者和24名男性血压正常者的血浆纤维蛋白原水平、白细胞计数和血小板计数。高血压患者的结果为：白细胞计数平均为5.45×10⁹/L，血小板计数平均为234.7×10⁹/L，血浆纤维蛋白原为4.13g/L。血压正常者的结果为：白细胞计数平均为4.83×10⁹/L，血小板计数平均为222.9×10⁹/L，血浆纤维蛋白原为3.27g/L。与血压正常者相比，高血压患者的血浆纤维蛋白原水平、白细胞计数和血小板计数更高，但只有血浆纤维蛋白原水平达到统计学显著差异（p<0.025）。
