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[粟粒性肺结核作为卡介苗免疫疗法治疗膀胱癌的并发症。病例报告]

[Miliary tuberculosis as a complication of BCG immunotherapy in cancer of the bladder. Case report].

作者信息

Arrese M, Ebel L, Hofmann E, Gaete P, Jara A, Cabrera K, Araos F, Del Río P, Valdivieso V

机构信息

Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica, Santiago de Chile.

出版信息

Rev Med Chil. 1992 Aug;120(8):910-3.

PMID:1340967
Abstract

Intravesical administration of BCG may be used as an ancillary immunotherapy after endoscopic resection for cancer of the bladder. Local side effects are usually mild. Here is reported a patient who developed miliary tuberculosis after this form of therapy. Radiologic studies of the thorax and liver biopsy confirmed the diagnosis. The patient recovered after treatment with anti-tuberculosis drugs (TA-81 scheme). Epithelial trauma may be invoked as an alteration facilitating this complication. Although it develops infrequently, patients with bladder cancer treated with BCG must be monitored for this complication.

摘要

卡介苗膀胱内给药可作为膀胱肿瘤内镜切除术后的辅助免疫疗法。局部副作用通常较轻。本文报告1例经此治疗后发生粟粒性结核的患者。胸部影像学检查和肝脏活检确诊了该诊断。患者经抗结核药物治疗(TA-81方案)后康复。上皮损伤可能是促使发生这一并发症的一种改变。尽管其发生率较低,但接受卡介苗治疗的膀胱癌患者必须监测这一并发症。

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