Arrese M, Ebel L, Hofmann E, Gaete P, Jara A, Cabrera K, Araos F, Del Río P, Valdivieso V
Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica, Santiago de Chile.
Rev Med Chil. 1992 Aug;120(8):910-3.
Intravesical administration of BCG may be used as an ancillary immunotherapy after endoscopic resection for cancer of the bladder. Local side effects are usually mild. Here is reported a patient who developed miliary tuberculosis after this form of therapy. Radiologic studies of the thorax and liver biopsy confirmed the diagnosis. The patient recovered after treatment with anti-tuberculosis drugs (TA-81 scheme). Epithelial trauma may be invoked as an alteration facilitating this complication. Although it develops infrequently, patients with bladder cancer treated with BCG must be monitored for this complication.
卡介苗膀胱内给药可作为膀胱肿瘤内镜切除术后的辅助免疫疗法。局部副作用通常较轻。本文报告1例经此治疗后发生粟粒性结核的患者。胸部影像学检查和肝脏活检确诊了该诊断。患者经抗结核药物治疗(TA-81方案)后康复。上皮损伤可能是促使发生这一并发症的一种改变。尽管其发生率较低,但接受卡介苗治疗的膀胱癌患者必须监测这一并发症。