[青少年型全身型类风湿关节炎与成人斯蒂尔病：临床病程比较]

[Juvenile systemic rheumatoid arthritis and adult-onset Still's disease: comparison of clinical course].

作者信息

Talesnik E, Leissner M, Jacobelli S

机构信息

Departamento de Pediatría e Inmunología Clínica, Escuela de Medicina, Pontificia Universidad Católica, Santiago de Chile.

出版信息

Rev Med Chil. 1992 Jun;120(6):638-43.

PMID:1341793

Abstract

The course of systemic juvenile rheumatoid arthritis (JRA) and that of Still's disease in the adult is unpredictable. The clinical course of 14 patients with JRA and 7 adults with Still's disease 6 months after onset was classified into 4 forms according to the persistence of joint manifestations after the cessation of systemic signs. a) monocyclic systemic form (5 children and 2 adults); b) polycyclic systemic form (3 children and 1 adult); c) monocyclic chronic joint form (3 children and 2 adults) and d) polycyclic chronic joint form (3 children, 2 adults). Seven of the 21 patients (5 children and 2 adults) developed joint sequelae, 5 with the polycyclic chronic joint form and 2 with the monocyclic chronic joint form. None of the patients with systemic forms, mono or polycyclic, developed sequelae. Thus, the course of patients with JRA and Still's disease may be used to predict development of joint sequelae.

摘要

系统性幼年类风湿性关节炎（JRA）及成人斯蒂尔病的病程是不可预测的。根据全身症状消退后关节表现的持续情况，将14例JRA患儿和7例成人斯蒂尔病患者发病6个月后的临床病程分为4种类型。a）单循环全身型（5名儿童和2名成人）；b）多循环全身型（3名儿童和1名成人）；c）单循环慢性关节型（3名儿童和2名成人）和d）多循环慢性关节型（3名儿童，2名成人）。21例患者中有7例（5名儿童和2名成人）出现关节后遗症，其中5例为多循环慢性关节型，2例为单循环慢性关节型。单循环或多循环全身型患者均无后遗症发生。因此，JRA和斯蒂尔病患者的病程可用于预测关节后遗症的发生。