Avcin Tadej, Silverman Earl D, Forte Vito, Schneider Rayfel
Division of Rheumatology, Department of Otolaryngology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
J Rheumatol. 2005 Dec;32(12):2429-31.
Nasal septal perforation has been well recognized in patients with various rheumatic diseases. To our knowledge, this condition has not been reported in children with systemic juvenile idiopathic arthritis (SJIA) or patients with adult onset Still's disease (AOSD). We describe 3 patients with persistent SJIA/AOSD who developed nasal septal perforation during the course of their disease. As illustrated by these cases, nasal septal perforation may develop as a rare complication of SJIA/AOSD and can be considered as part of the clinical spectrum of the disease. In one case the nasal septal perforation was associated with vasculitis.
鼻中隔穿孔在各种风湿性疾病患者中已得到充分认识。据我们所知,这种情况在系统性幼年特发性关节炎(SJIA)患儿或成人斯蒂尔病(AOSD)患者中尚未见报道。我们描述了3例持续性SJIA/AOSD患者,他们在疾病过程中出现了鼻中隔穿孔。如这些病例所示,鼻中隔穿孔可能作为SJIA/AOSD的一种罕见并发症出现,并可被视为该疾病临床谱的一部分。在1例病例中,鼻中隔穿孔与血管炎相关。