[Mutagenic changes in medical personnel occupationally exposed to antineoplastic drugs].

Not so long ago the unfavourable influence of antineoplastic drugs on personnel exposed to them was reported. Since then research has been carried out with the aim of clarifying and objectivizing this occupational danger. Agreement was reached on the need for measures of protection at work and regular medical check-ups of personnel exposed to these cancerogenic substances, which can also have a mutagenic and teratogenic effect. This paper presents the possible consequences of the effect of antineoplastic drugs in long-term exposure to low concentrations, and the means of protection from the unfavourable effect of exposure. In our country such means of protection and regular medical check-ups of personnel are not carried out in any oncological department, which is a serious oversight, particularly if we accept the fact that today 70-90% of all carcinomas are due to agents within our environment and diet.