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1909年莱珀所描述的小唇蛔线虫(线虫纲:蛔科)在小白鼠和猫体内的实验性异寄主周期

Experimental heteroxenous cycle of Lagochilascaris minor Leiper, 1909 (Nematoda: Ascarididae) in white mice and in cats.

作者信息

Volcan G S, Medrano C E, Payares G

机构信息

Departamento de Parasitología y Microbiología, Escuela de Medicina, Universidad de Oriente, Ciudad Bolívar, Venezuela.

出版信息

Mem Inst Oswaldo Cruz. 1992 Oct-Dec;87(4):525-32. doi: 10.1590/s0074-02761992000400010.

DOI:10.1590/s0074-02761992000400010
PMID:1343667
Abstract

Reports of natural infections of sylvatic carnivores by adult worms of species similar to Lagochilascaris minor in the Neotropical region led to attempts to establish experimental cycles in laboratory mice and in cats. Also, larval development was seen in the skeletal muscle of an agouti (Dasyprocta leporina) infected per os with incubated eggs of the parasite obtained from a human case. In cats, adult worms develop and fertile eggs are expelled in the feces; in mice, larval stages of the parasite develop, and are encapsulate in the skeletal muscle, and in the adipose and subcutaneous connective tissue. From our observations, we conclude that the larva infective for the mouse is the early 3rd stage, while for the final host the infective form is the later 3rd stage. A single moult was seen in the mouse, giving rise to a small population of 4th stage larvae, long after the initial infection.

摘要

新热带地区野生食肉动物被类似于小唇蛔属成虫自然感染的报告促使人们尝试在实验室小鼠和猫中建立实验循环。此外,在一只经口感染从人类病例获得的寄生虫孵化卵的刺豚鼠(Dasyprocta leporina)的骨骼肌中观察到了幼虫发育。在猫中,成虫发育并在粪便中排出受精卵;在小鼠中,寄生虫的幼虫阶段发育,并包裹在骨骼肌、脂肪和皮下结缔组织中。根据我们的观察,我们得出结论,对小鼠具有感染性的幼虫是早期第三阶段,而对终末宿主具有感染性的形式是晚期第三阶段。在初次感染很久之后,在小鼠中观察到一次蜕皮,产生了一小群第四阶段幼虫。

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