扬茨青少年肌阵挛癫痫：60例临床观察

Juvenile myoclonic epilepsy of Janz: clinical observations in 60 patients.

作者信息

Canevini M P, Mai R, Di Marco C, Bertin C, Minotti L, Pontrelli V, Saltarelli A, Canger R

机构信息

University of Milan, Chair of Clinical Neurophysiology, S. Paolo Hospital, Italy.

出版信息

Seizure. 1992 Dec;1(4):291-8. doi: 10.1016/1059-1311(92)90039-4.

DOI:10.1016/1059-1311(92)90039-4

PMID:1344779

Abstract

We studied 60 patients with juvenile myoclonic epilepsy (JME). There was a high positive family history for epilepsy (33.3%). Age at onset of epilepsy ranged from 4 to 18 years with an average of 13.9 years. 88.3% of patients were seizure-free. The most effective drug was valproate. In eight patients drug withdrawal was attempted but all patients relapsed during a follow-up period of 1 year. Video-EEG studies were performed in eight newly diagnosed patients; myoclonic jerks were recorded in five patients.

摘要

我们研究了60例青少年肌阵挛性癫痫（JME）患者。癫痫家族史阳性率很高（33.3%）。癫痫发病年龄在4至18岁之间，平均为13.9岁。88.3%的患者无癫痫发作。最有效的药物是丙戊酸盐。8例患者尝试停药，但在1年的随访期内所有患者均复发。对8例新诊断患者进行了视频脑电图研究；5例患者记录到肌阵挛抽搐。